Arsenal face Chelsea at Wembley on Saturday looking to salvage silverware from a campaign that has seen them miss out on Champions League qualification for the first time in 20 seasons.
And they are hopeful forward Sanchez will come through fitness tests on a hamstring problem in order to play against Antonio Conte's men.
However, Gabriel is definitely out after being taken off on a stretcher against Everton on Sunday with a knee injury, while Mustafi is "still sick" and doubtful with a suspected concussion.
That leaves Arsenal with big problems in defence given Laurent Koscielny is suspended after being sent off in the Everton match.
Rob Holding and Per Mertesacker – who has not started a match for over a year – are the club's only other senior centre-backs.
"Alexis is alright," Wenger said at his pre-match media conference.
"We will see as he needs to go through some tests. But knowing the player, knowing his character and commitment to the club - which I don't question at all - he will do absolutely everything to be fit for Saturday.
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